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In: Notter RH, Finkelstein JN,Holm BA (eds) Lung injury: mechanisms, pathophysi-ology, and therapy. When liver is homogenized and ruptured cells aredifferentially centrifuged, fragments of the endoplasmicreticulum with xenobiotic-metabolizing capabilities are iso-lated in the fraction called microsomes (artifacts of cell dis-ruption), a term often used to identify the cellular location ofxenobiotic-metabolizing enzymes.

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